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Tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it mimics two natural hormones:
GIP (glucose-dependent insulinotropic polypeptide)
GLP-1 (glucagon-like peptide-1)
Weight Loss Benefits
In clinical studies, patients lost an average of 15–22.5% of their body weight, depending on the dose. That’s more than many other GLP-1 medications like Semaglutide (Ozempic, Wegovy).
How It’s Taken
Once-weekly subcutaneous injection
Available in pre-filled pens with varying doses (e.g., 2.5mg, 5mg, up to 15mg)
Dosing is typically titrated (increased gradually) to reduce side effects
Possible Side Effects
Most are gastrointestinal and mild to moderate:
Nausea
Diarrhea or constipation
Decreased appetite
Fatigue
Injection site reactions
Contraindications / Warnings
Personal or family history of medullary thyroid carcinoma (MTC)
MEN2 syndrome
Pregnant or breastfeeding women should not use it
Tirzepatide is a dual GIP and GLP-1 receptor agonist, meaning it mimics two natural hormones:
GIP (glucose-dependent insulinotropic polypeptide)
GLP-1 (glucagon-like peptide-1)
Weight Loss Benefits
In clinical studies, patients lost an average of 15–22.5% of their body weight, depending on the dose. That’s more than many other GLP-1 medications like Semaglutide (Ozempic, Wegovy).
How It’s Taken
Once-weekly subcutaneous injection
Available in pre-filled pens with varying doses (e.g., 2.5mg, 5mg, up to 15mg)
Dosing is typically titrated (increased gradually) to reduce side effects
Possible Side Effects
Most are gastrointestinal and mild to moderate:
Nausea
Diarrhea or constipation
Decreased appetite
Fatigue
Injection site reactions
Contraindications / Warnings
Personal or family history of medullary thyroid carcinoma (MTC)
MEN2 syndrome
Pregnant or breastfeeding women should not use it