Epithalon (Epitalon)
Epithalon is a synthetic tetrapeptide made of four amino acids (Ala-Glu-Asp-Gly) originally developed in Russia and widely studied in basic research focused on aging and cellular biology. It is an analog of epithalamin, a peptide produced by the pineal gland.
In research contexts, epithalon is typically provided as lyophilized peptide powder in vials that are reconstituted with bacteriostatic water before use.
Benefits
In laboratory and animal research, epithalon has been associated with:
🔬 Cellular & Longevity Effects
Activation of telomerase, an enzyme that helps preserve and lengthen telomeres — protective caps on chromosome ends, which shorten with age. This is a key mechanism linked to cellular aging.
Support for DNA integrity and cell division capacity in models.
🌙 Pineal & Circadian Regulation
Potential enhancement of melatonin production and normalization of circadian rhythms, which can support sleep quality and hormone balance.
🛡️ Immune & Oxidative Support
Built-in antioxidant activity may help reduce oxidative stress and damage to cells.
May support immune function and overall cellular resilience.
Research
Although clinical evidence is limited, epithalon is described in some research models as potentially influencing longevity markers, sleep, oxidative stress, and vitality — typically studied in animal or cellular settings rather than large human trials.
User anecdotes also mention sleep benefits or subtle cognitive and vitality responses, though these are individual reports without controlled clinical validation.
Epithalon is a synthetic peptide studied for telomerase activation, cellular longevity mechanisms, circadian regulation, and immune support
Epithalon is a synthetic tetrapeptide made of four amino acids (Ala-Glu-Asp-Gly) originally developed in Russia and widely studied in basic research focused on aging and cellular biology. It is an analog of epithalamin, a peptide produced by the pineal gland.
In research contexts, epithalon is typically provided as lyophilized peptide powder in vials that are reconstituted with bacteriostatic water before use.
Benefits
In laboratory and animal research, epithalon has been associated with:
🔬 Cellular & Longevity Effects
Activation of telomerase, an enzyme that helps preserve and lengthen telomeres — protective caps on chromosome ends, which shorten with age. This is a key mechanism linked to cellular aging.
Support for DNA integrity and cell division capacity in models.
🌙 Pineal & Circadian Regulation
Potential enhancement of melatonin production and normalization of circadian rhythms, which can support sleep quality and hormone balance.
🛡️ Immune & Oxidative Support
Built-in antioxidant activity may help reduce oxidative stress and damage to cells.
May support immune function and overall cellular resilience.
Research
Although clinical evidence is limited, epithalon is described in some research models as potentially influencing longevity markers, sleep, oxidative stress, and vitality — typically studied in animal or cellular settings rather than large human trials.
User anecdotes also mention sleep benefits or subtle cognitive and vitality responses, though these are individual reports without controlled clinical validation.
Epithalon is a synthetic peptide studied for telomerase activation, cellular longevity mechanisms, circadian regulation, and immune support

