Estradiol vaginal inserts are low-dose hormone therapy products designed to deliver estradiol (a form of estrogen) directly to the vaginal tissues. They’re typically used to ease symptoms of low estrogen in and around the vagina — especially after menopause or during perimenopause.
These include prescription products like Imvexxy Vaginal Inserts, The HRT Club Vaginal Inserts, and several generic vaginal estradiol inserts. The active hormone helps restore moisture, tissue health, and comfort.
Estradiol vaginal inserts are clinically used for:
Reducing vaginal dryness, itching, burning, and irritation.
Treating painful sexual intercourse (dyspareunia) due to vaginal atrophy caused by declining estrogen.
Encouraging thicker, more elastic vaginal tissue and improved lubrication.
May help with urinary symptoms like urgency or discomfort associated with low estrogen.
Because the hormone is placed locally, systemic absorption tends to be much lower than with oral estrogen, focusing effects mainly on genital tissues.
